DNA Vaccine Treatment in Dogs Experimentally Infected with Trypanosoma cruzi

Table 2

Abnormal electrocardiographic features in dogs experimentally infected with T. cruzi and treated with the DNA vaccine at 3, 6, and 12 months postinfection (mpi).

Group	Suggested pathological conditions by EKG recordings [78, 79]	Affected dogs (dogs/) at 3 mpi	Affected dogs (dogs/) at 6 mpi	Affected dogs (dogs/) at 12 mpi
Inf/SS mock-treated	AV block+infarction	20% (1/5)
	Ischemia	20% (1/5)
	MEAD to the left+LBBB+infarction+ventricle enlargement	20% (1/5)
	MEAD to the right+RBBB+infarction+ventricle enlargement		60% (3/5)
	Arrhythmia+MEAD to the left+ventricle enlargement			20% (1/5)
	Ischemia+MEAD to the right+ventricle enlargement			60% (3/5)
pBCSSP4	AV block		20% (1/5)
	LBBB	20% (1/5)
	MEAD to the right+RBBB+infarction	20% (1/5)
	MEAD to the left+LBBB+AV block	20% (1/5)
	LBBB+infarction+ischemia	40% (2/5)	20% (1/5)
	RBBB+ischemia			40% (2/5)
pBCSP	AV block	20% (1/5)
	Infarction	20% (1/5)
	Infarction+ischemia	20% (1/5)	20% (1/5)
	Arrhythmia+AV block			20% (1/5)
Mixture	AV block+infarction+RBBB	20% (1/5)
	Ischemia	20% (1/5)	20% (1/5)
	Arrhythmia+ischemia		20% (1/5)
	AV block+ischemia		20% (1/5)	20% (1/5)
pBK-CMV	Arrhythmia+ischemia		20% (1/5)
	MEAD to the left+ventricle enlargement	40% (2/5)
	MEAD to the left+LBBB+infarction+ventricle enlargement	20% (1/5)
	Arrhythmia+MEAD to the right+ventricle enlargement+ischemia		20% (1/5)
	MEAD to the right+RBBB+ventricle enlargement+infarction+ischemia		40% (2/5)
	Ventricle enlargement			20% (1/5)
	Arrhythmia+MEAD to the left+ventricle enlargement			20% (1/5)
	Arrhythmia+ventricle enlargement+ischemia+MIMI			20% (1/5)

Group descriptions are shown in Table 1. mpi = months postinfection; Inf = infected; AV = atrioventricular; LBBB = left bundle branch block; RBBB = right bundle branch block; MEAD = mean electrical axis deviation; MIMI = microscopic intramural myocardial infarction.