Research Article
Clinical Features and Outcomes of Neuropsychiatric Systemic Lupus Erythematosus in China
Table 1
Baseline characteristics of the 194 patients with NPSLE.
| | Characteristics | Value () (%) |
| | Female | 180 (92.8) | | Age (years) | | | SLE duration (years), | | | NP duration (years), | | | >1 NP subtype | 71 (36.6) | | Subtypes of NPSLE | | | Central nervous system involvement | 184 (94.8) | | Seizure | 71 (36.6) | | Acute confusional state | 49 (25.3) | | Cerebrovascular disease | 30 (15.5) | | Headache | 27 (13.9) | | Psychosis | 22 (11.3) | | Cognitive impairment | 19 (9.8) | | Mood disorder | 17 (8.8) | | Demyelination | 6 (3.1) | | Dyskinesia | 1 (0.5) | | Myelitis | 5 (2.6) | | Aseptic meningitis | 4 (2.1) | | Anxiety disorder | 3 (1.5) | | Peripheral nervous system involvement | 21 (10.8) | | Cranial neuropathy | 8 (15.5) | | AIDP | 3 (1.5) | | Single/multiplex mononeuropathy | 5 (3.6) | | Polyneuropathy | 5 (4.1) | | Increased CSF pressure | 73 (37.6) | | Increased CSF protein | 78 (40.2) | | Treatment | | | Steroid pulse | 146 (75.3) | | CTX | 179 (92.3) | | MMF | 9 (4.6) |
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NPSLE: neuropsychiatric systemic lupus erythematosus; AIDP: acute inflammatory demyelinating polyradiculoneuropathy; CSF: cerebrospinal fluid; CTX: cyclophosphamide; MMF: mycophenolate mofetil.
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