Research Article

Neutrophil-to-Lymphocyte Ratio (NLR) Predicts PD-1 Inhibitor Survival in Patients with Metastatic Gastric Cancer

Table 1

The characteristics of the analyzed patients in different groups.

Characteristics value
%%

No. patients8156
Gender (%)
 Male5972.8%3969.6%0.685
 Female2227.2%1730.4%
(%)
 <593543.2%2137.5%0.505
 ≥594656.8%3562.5%
PD-L1 (%)
 Positive1417.3%1119.6%0.227
 Negative1417.3%1526.8%
 Unknown5365.4%3053.6%
ECOG PS (%)
 02632.1%1017.9%0.508
 14353.1%4376.8%
 ≥21214.8%35.4%
Tumor_location (%)
 Cardia2530.9%1425.0%0.448
 Body/fundus5061.7%3766.1%
 Pylorus67.4%58.9%
Histological_differentiation (%)
 Poorly4049.4%3155.4%0.473
 Moderately3745.7%2341.1%
 Well44.9%23.6%
No. of metastasis organs (%)
 <22429.6%1119.6%0.189
 ≥25770.4%4580.4%
Liver metastasis (%)
 Yes4960.5%3155.4%0.55
 No3239.5%2544.6%
Smoking_history (%)
 Smoke3037.0%2951.8%0.088
 Never smoked5163.0%2748.2%
Drinking_history (%)
 Drink3846.9%3562.5%0.073
 Never drinked4353.1%2137.5%
Anti-PD-1 treatment line (%)
 First line4251.9%2442.9%0.421
 Second line3442.0%3053.6%
 Third line56.2%23.6%
Treatment type (%)
 Anti-PD-1 monotherapy89.9%712.5%0.741
 Combination therapy
 Anti-PD-1 plus chemotherapy5567.9%3766.1%
 Anti-PD-1 plus antiangiogenic therapy1822.2%1221.4%

ECOG PS: Eastern Cooperative Oncology Group Performance Status; PD-L1: programmed death ligand-1.