Human Adenovirus Serotype 3 Infection Modulates the Biogenesis and Composition of Lung Cell-Derived Extracellular Vesicles

Figure 3

The effect of HAdV3 infection on intracellular trafficking GTPase. (a) Dot blot analysis showing expression of Rab5, Rab7, and Rab35 after 48 h and 72 h infection. EVs were probed for the presence of Rab proteins. (b) (i) Graphs showing quantification of Rab5 level after 48 h and (ii) 72 h of infection. (c) (i) Rab7 after 48 h and (ii) 72 h of infection. (d) (i) Rab35 after 48 h and (ii) 72 h of infection. Data show the from three independent experiments. Dots shown in the figure are representative of four independent experiments. Data shows the from four independent experiments and performed using one-way analysis of variance (ANOVA) with Tukey post hoc analysis. Statistical significance is indicated by the as follows: , , , and .

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