Human Adenovirus Serotype 3 Infection Modulates the Biogenesis and Composition of Lung Cell-Derived Extracellular Vesicles

Figure 7

The effect of HAdV3 infection on proinflammatory interleukin and interferon. (a) Dot blot analysis showing expression of IL-1β and TLR7 after 48 h and 72 h infection. EVs were probed for the expression of IL-1β and TLR7 proteins. (b) Western blot analysis showing Hsp70, CD9, and IRF8 expression after 48 h and 72 h of infection. (c) (i) Graph showing quantification of IL-1β after 48 h and (ii) 72 h of infection. (d) (i) IRF-3 after 48 h and (ii) 72 h of infection. Dots shown in the figure are representative of four independent experiments. Data shows the from four independent experiments and performed using one-way analysis of variance (ANOVA) with Tukey post hoc analysis. Statistical significance is indicated by the as follows, , , and .

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