|
| Human | Mouse |
| GEO ID | GSE17470 | GSE63067 | GSE35961 | GSE63027 | GSE63027 | GSE53381 |
| Comparison | NASH vs. healthy | NASH vs. healthy | MCD+HFD vs. NCD | GNMT-KO vs. WT | MAT1A-KO vs. WT | HFCD vs. NCD |
|
| Pathways | | | | | | |
| Superpathway of geranylgeranyl diphosphate biosynthesis I (via mevalonate) | | | | | | |
| Estrogen biosynthesis | | | | | ↑ | |
| Acetone degradation I (to methylglyoxal) | | | | | ↑ | |
| Mevalonate pathway I | | | | | ↑ | |
| Tryptophan degradation III (eukaryotic) | | | | | | |
| Antioxidant action of vitamin C | | | | ↑ | | |
| Oxidative phosphorylation | | | | ↑ | | |
| Glutaryl-CoA degradation | | | | ↑ | | |
| Valine degradation I | | | | ↑ | | |
| Isoleucine degradation I | | | | ↑ | | |
| RhoA signaling | | | | ↑ | | |
| Mitotic roles of polo-like kinase | | | | ↑ | | |
| Triacylglycerol biosynthesis | | | | ↑ | | |
| TCA cycle II (eukaryotic) | | | | ↑ | | |
| Role of CHK proteins in cell cycle checkpoint control | | | | ↑ | | |
| Sumoylation pathway | | | | ↑ | | |
| Apelin adipocyte signaling pathway | | ↑ | | ↑ | | |
| Glutathione-mediated detoxification | | | | ↑ | | |
| Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate | | | | ↑ | | |
| CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | | | | ↑ | | |
| EIF2 signaling | | | | ↑ | | |
| tRNA charging | | | | ↑ | | |
| Folate transformations I | | | | ↑ | | |
| Endocannabinoid cancer inhibition pathway | | | | | ↑ | |
| Pyrimidine ribonucleotide interconversion | | | | | ↑ | |
| Pyrimidine ribonucleotide de novo biosynthesis | | | | | ↑ | |
| NAD salvage pathway II | | | | | ↑ | |
| PPARα/RXRα activation | | | | | ↑ | |
| NRF2-mediated oxidative stress response | | ↑ | | | ↑ | |
| Glutathione redox reactions I | | | | | ↑ | |
| Pancreatic adenocarcinoma signaling | | | | | ↑ | |
| Estrogen-mediated S-phase entry | | | | | ↑ | |
| Type II diabetes mellitus signaling | | | | | ↑ | |
| PCP pathway | | | | | ↑ | |
| PDGF signaling | | | | | ↑ | |
| NF-κB signaling | | ↑ | | | | |
| Neuroinflammation signaling pathway | | ↑ | | | | |
| Tec kinase signaling | | ↑ | | | | |
| B cell receptor signaling | | ↑ | | | | |
| Osteoarthritis pathway | | ↑ | | | | |
| Th17 activation pathway | | ↑ | | | | |
| Role of pattern recognition receptors in recognition of bacteria and viruses | | ↑ | | | | |
| Apelin endothelial signaling pathway | | ↑ | | | | |
| Cholecystokinin/gastrin-mediated signaling | | ↑ | | | | |
| T cell exhaustion signaling pathway | | ↑ | | | | |
| Endothelin-1 signaling | | ↑ | | | | |
| B cell activating factor signaling | | ↑ | | | | |
| RANK signaling in osteoclasts | | ↑ | | | | |
| Toll-like receptor signaling | | ↑ | | | | |
| Renin-angiotensin signaling | | ↑ | | | | |
|
