Yangxue Jiedu Fang Ameliorates Psoriasis by Regulating Vascular Regression via Survivin/PI3K/Akt Pathway

Figure 3

Protein levels and localization of Survivin, as detected by Western blot and immunochemical staining and immunofluorescence analysis. Survivin expression was evaluated by Western blotting (a). The expression of Survivin was increased in the model groups compared with the control groups, and YXJD inhibited the expression of Survivin in the lesions of IMQ-induced PA mice (b). Survivin protein expression in the mice was measured by immunochemical staining and immunofluorescence analysis (c). Double immunofluorescence staining for CD31 (green) and Survivin (red) in a representative skin sample from the 4 groups are shown. Nuclei were counterstained with DAPI (blue).

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