Phenotype of Peripheral NK Cells in Latent, Active, and Meningeal Tuberculosis

Figure 1

Major NK cell subpopulations in patients with TBM. (a) Flow cytometry gating strategy for the analysis of circulating NK cells in peripheral blood mononuclear cell (PBMC) samples from healthy controls (HC, ), individuals with latent TB infection (LTBI, ), patients with active pulmonary TB (PTB, ), and patients with tuberculous meningitis (TBM, ). (b) Percentage of lymphocytes from total PBMCs. (c, d) Percentage of NK cells from total lymphocytes. (e) Analysis of major NK cell subpopulations in the blood. (f) Percentage of CD56^brightCD16^- NK cells. (g) Percentage of CD56^dimCD16⁺ NK cells. Differences between groups were analyzed using the Kruskal-Wallis test and the post hoc Dunn’s test for multiple comparisons. The data shown represent the mean (±SE) values. , , and .

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