Research Article

Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice

Figure 3

Effects of camptothecin (CPT) on the inflammatory response of DSS-induced ulcerative colitis (UC) in mice. (a) Myeloperoxidase (MPO) activity assay. The protein levels of (b) IL-1β, (c) IL-6, and (d) TNF-α were detected using ELISA. Western blot assay of (e, f) inducible nitric oxide synthase (iNOS) and (e, g) cyclooxygenase-2 (COX-2). The relative protein levels were quantified by scanning densitometry and normalized to the protein level of β-actin. Values are presented as (, , and vs. the DSS group).
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