Research Article
Upregulation of lnc-ZNF281 Inhibits the Progression of Glioma via the AKT/GSK-3β/β-Catenin Signaling Pathway
Figure 5
Overexpression of lnc-ZNF281 inhibited the AKT/GSK-3β/β-catenin pathway in glioma cells. (a–c) The Western blot results showed that overexpression of lnc-ZNF281 decreased the protein expression levels of p-AKT and p-GSK-3β, while had no effect on total AKT and GSK-3β protein levels. (d, e) Results of Western blot and qPCR demonstrated that increased lnc-ZNF281 suppressed the expression of β-catenin mRNA and protein. .
(a) |
(b) |
(c) |
(d) |
(e) |