TEX10 Promotes the Tumorigenesis and Radiotherapy Resistance of Urinary Bladder Carcinoma by Stabilizing XRCC6

Figure 6

TEX10 promotes NHEJ efficiency. (a) Diagram of NHEJ. Scissors indicate the cut sites of I-Sce I. The cut sites were cleaved after I-Sce I expression. GFP was expressed after NHEJ repair completion. (b) Fluorescent observation of DSB from T24 cells as suggested after I-Sce I expression. (c, d) Efficiency of the NHEJ repairs analyzed with flow cytometry. The percentage of GFP expression was regarded as repair completion for NHEJ repair tests. Shown is the . ; <0.01; <0.001, Student’s -test. (e) T24 cells received the treatment by using increasing doses of IR and subjected to survival tests by CCK8 test. Shown is the . ; <0.01; <0.001, Student’s -test.

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