Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice

Figure 1

The elements of traditional Chinese medicine NBXH and its flow chart of immunotherapy in a mice model. (a) Schematic diagram of the six natural plants of NBXH. (b) Three days before immunotherapy, 53 female BALB/c mice were infected by M. tuberculosis H37Rv strain with CFUs per mouse. Then, three mice were sacrificed to determine whether the infection model had been successfully constructed. The remaining mice were randomly assigned to five groups and treated with water (negative control); INH (positive control); and NBXH-L, NBXH-M, or NBXH-H by intragastric administration five times in one week. In addition, as a blank control, ten normal mice without any treatment were kept in the same condition. After 91 days of initial immunotherapy, mice were sacrificed, and their lungs, livers, spleens, and blood were collected to evaluate the effect of immunotherapy or identify GE genes.

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