Research Article
Chinese Traditional Medicine NiuBeiXiaoHe (NBXH) Extracts Have the Function of Antituberculosis and Immune Recovery in BALB/c Mice
Table 4
The significant downregulated genes after NBXH-H treatment.
| | GenBank accession | Gene name | Groups | Gene ontology annotations | | Water vs. NC | INH vs. Water | NBXH-H vs. Water | Cellular component | Molecular function | Biological process |
| | NM_008206 | H2-Oa | 2 (↑) | 4 (↓) | 54 (↓) | Cell part | No | Cellular process | | NM_175397 | Sp110 | 4 (↑) | 4 (↓) | 50 (↓) | Intracellular part | Binding molecular function | Cellular metabolic process | | NM_033324 | Dgcr8 | No | No | 37 (↓) | Intracellular part | Binding molecular function | Metabolic process | | NM_026605 | Sympk | No | No | 30 (↓) | Intracellular part | No | No | | NM_008080 | B4galnt1 | No | 2 (↓) | 29 (↓) | Intracellular part | Catalytic activity | Metabolic process | | NM_016670 | Pknox1 | 3 (↑) | 2 (↓) | 29 (↓) | Intracellular part | Binding molecular function | Cellular metabolic process | | NM_027425 | Rufy2 | No | 4 (↓) | 27 (↓) | Intracellular part | Binding molecular function | No | | NM_027453 | Btf3l4 | 2 (↑) | 3 (↓) | 26 (↓) | No | No | No | | M22934 | — | No | 4 (↓) | 25 (↓) | — | — | — | | X56177 | — | 3 (↑) | 7 (↓) | 23 (↓) | — | — | — | | U88691 | — | 2 (↑) | 3 (↓) | 22 (↓) | — | — | — | | NM_009157 | Map2k4 | 2 (↑) | No | 22 (↓) | Intracellular part | Binding molecular function | Cellular metabolic process | | NM_178688 | Ablim1 | 4 (↑) | No | 21 (↓) | Intracellular part | Binding molecular function | Cellular metabolic process | | NM_138596 | Med10 | No | No | 21 (↓) | Intracellular part | Transcription cofactor activity | Metabolic process | | NM_176933 | Dusp4 | 2 (↑) | No | 21 (↓) | Intracellular part | Catalytic activity | Cellular metabolic process | | NM_011513 | Med22 | No | No | 21 (↓) | Intracellular part | Transcription cofactor activity | Metabolic process | | NM_033078 | Klrk1 | No | No | 20 (↓) | Cell part | Binding molecular function | Metabolic process | | NM_026279 | Bend5 | No | No | 20 (↓) | Intracellular part | No | No |
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