Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus

Figure 1

IL-33 expression is elevated, and Th1/Th2 ratio is imbalance in infants with acute bronchiolitis. (a) ELISA assay was used to detect the production of IL-33 in serum. (b, c) The levels of Th2-related cytokines IL-4 and IL-10 were examined by ELISA assay. (d, e) The levels of Th1-related cytokines IL-2 and INF-γ were examined by ELISA assay. (f) Cell flow cytometry was used to detect the ratio of Th1/Th2 cells. (g) ELISA assay was used to detect the production of ST2 in serum. (h) Correlation analysis is used to calculate the correlation between IL-33 and ST2 in serum. All data were expressed as the (). Each value of , , and was deem to have significant differences.

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