Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus

Figure 3

RSV-induced mouse model is attenuated after inhibition of NF-κB/IL-33/ST2 pathway. (a) Immunohistochemical analysis of IL-33, ST2, and p65 abundance in saline-exposed control mice (NC); RSV-treated mice (RSV) was performed (original magnification ×400, scale bar 100 μm) and scored (right graph). (b) H&E staining of lung tissue in different group mice was analyzed by Image-proplus 6.0 (original magnification ×400). The data are presented as and were analyzed by Student’s -test (NC group, ; RSV group, ; ; ; ; ). Each value of , , and was considered to be significant differences.

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