Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus

Figure 4

Macrophages are important sources of IL-33 and are regulated by NF-κB pathway in RSV-induced mice. (a) The number of alveolar macrophages, lymphocyte, and eosinophils in BAL of mice. (b) Flow cytometry analysis was performed to sort alveolar macrophages at different times after RSV infection. (c) Flow cytometry analysis was performed to sort alveolar macrophages at different times after RSV + PDTC treatment. (d) The IL-33 expression in alveolar macrophages at different times after RSV + PDTC treatment was examined by RT-PCR analysis. All data were expressed as the (). Each value of , , and was considered to be significant differences.

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