DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis

<div>DGAT1 promotes proliferation, colonization, and metastasis of ovarian cancer. (a) CCK-8 cell proliferation assay was carried out using OVCAR-5 and PEO4 cells with sh-Ctrl, sh-DGAT1. (b) Colony formation assay was performed using OVCAR-5 and PEO4 cells with sh-Ctrl, sh-DGAT1. (c) Transwell migration assay was conducted using OVCAR-5 and PEO4 cells with sh-Ctrl, sh-DGAT1. (d) Tumor model is established using sh-Ctrl, sh-DGAT1 OVCAR-5 transfected cells (<svg height="11.7782pt" id="M19" style="vertical-align:-3.42938pt" version="1.1" viewbox="-0.0498162 -8.34882 38.2627 11.7782" width="38.2627pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 -12C351 3 429 48 483 105C543 168 570 242 570 304ZM482 289C482 161 380 33 304 33C278 33 248 51 233 69L303 396C326 400 352 403 369 403C428 403 482 380 482 289Z"></path></g><g transform="matrix(.013,0,0,-0.013,11.342,0)"><path d="M531 285V335L57 550V494L473 310L57 127V71L531 285ZM531 -40V10H57V-40H531Z"></path></g><g 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Journal of Immunology Research

fig3

Figure 3

Figure 3: DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis 