Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity

Table 1

Baseline characteristics of the study population.

Characteristic	HD ()	MDR-TB ()	DS-TB ()	value (MDR vs. DS)
Age (years), median (IQR)	27 (19-40)	41 (36-47)	38 (27-52)	0.717
Male gender, (%)	3 (50%)	12 (86%)	9 (81%)	0.604
DM2, (%)	0 (0%)	10 (71%)	5 (45%)	0.183
Alcoholism, (%)	0 (0%)	6 (43%)	2 (18%)	0.190
Smoking, (%)	0 (0%)	3 (21%)	3 (27%)	0.548
BMI (kg/m^2), median (IQR)	23 (21-26)	24 (18-25)	23 (20-25)	0.837
Previous TB treatment, (%)	—	14 (100%)	1 (9%)	<0.005
Time of first TB diagnosis (years), median (IQR)	—	6 (2-8)	2	<0.005

Differences in categorical and continuous variables were analyzed with the Fisher exact test and Mann–Whitney test, respectively. Values of were considered significant. BMI: body mass index; DM2: type 2 diabetes mellitus; DS-TB: drug-susceptible tuberculosis; IQR: interquartile range (IQR); MDR-TB: multidrug-resistant tuberculosis. Data from one patient.