Leukocytes from Patients with Drug-Sensitive and Multidrug-Resistant Tuberculosis Exhibit Distinctive Profiles of Chemokine Receptor Expression and Migration Capacity
Table 2
Laboratory characteristics of the study population.
Characteristic
Total ()
MDR-TB ()
DS-TB ()
value (MDR vs. DS)
Leukocytes, median (IQR), (RV cells/mm3)
10 (9-11)
10 (8-11)
10 (9-11)
0.970
Neutrophils, median (IQR), (RV cells/mm3)
6.9 (6-8)
7 (5-7)
6.9 (6-8)
0.851
Lymphocytes, median (IQR), (RV 1-4 x 103 cells/mm3)
1.5 (1.3-2.1)
1.5 (1.3-2.1)
1.5 (0.9-2)
0.548
Monocytes, median (IQR), (RV cells/mm3)
0.6 (0.4-0.9)
0.6 (0.5-0.8)
0.9 (0.3-0.9)
0.852
Platelets, median (IQR), (RV cells/mm3)
325 (276-362)
333 (383-427)
299 (270-325)
0.204
Hemoglobin, median (IQR), (RV 11.5-17 mg/dl)
13 (12-14)
14 (12-16)
12.6 (12-14)
0.455
Glucose, median (IQR), (RV 74-106 mg/dl)
134 (96-150)
117 (87-150)
138 (107-229)
0.262
Albumin, median (IQR), (RV 3.5-4.8 mg/dl)
3.5 (2.8-3.8)
3.6 (3.1-3.8)
2.8 (2.6-3.5)
0.117
LDH, median (IQR), (RV 98-192 U/l)
158 (136-196)
155 (141-194)
183 (119-198)
0.868
Mann–Whitney test values < 0.05 were considered as significant. LDH: lactate dehydrogenase; DS-TB: drug-susceptible tuberculosis; IQR: interquartile range; MDR-TB: multidrug-resistant tuberculosis. RV: reference value (provided by the institutional Clinical Laboratory).
