Research Article
Blocking the Hepatic Branch of the Vagus Aggravates Hepatic Ischemia-Reperfusion Injury via Inhibiting the Expression of IL-22 in the Liver
Figure 3
Hepatic vagotomy reduces hepatic IL-22 production induced by ischemia-reperfusion injury. (a) Typical immunohistochemical staining pictures of liver tissues in the three groups of mice at 12 h postreperfusion (×200 magnification). (b) The positive area of IL-22 staining is shown as brown, and the IL-22+ hepatocyte/total hepatocyte ratio is calculated. (c, d) Expressions of IL-22 (6 h) and IL-22Rα1 mRNA in different liver tissues. (e, f) Serum IL-22 concentration and the expression of IL-22 protein in the livers of two groups at different time points after reperfusion (; . Compared with the SHI group: #).
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