Seroconversion and Abundance of IgG Antibodies against S1-RBD of SARS-CoV-2 and Neutralizing Activity in the Chilean Population

Figure 3

Convalescent plasma donors and IgG antiviral levels. Anti-RBD IgG concentration (a) and neutralizing activity (b) were determined at different days of convalescence. In (c), representative cases with a similar IgG concentration and decreasing neutralizing antibodies. (d) Neutralization activity and IgG levels; average neutralizing activity was represented for stratified high () and low () IgG anti-RBD cases based on the 75th percentile. The results are presented as the , and statistical differences from the Mann–Whitney test are shown. (e) 2×2 contingence analysis for high/low antibody levels (P75) and high/low neutralizing activity (median ID80). 75th percentile (P75) and IgG cut-off are indicated in red and black dotted lines, respectively.

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