Research Article
TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38-/- Sepsis Mice
Figure 6
The expression of GSDMD was detected by Western blot. The expressions of GSDMD in the liver of WT, CD38-/-, and CD38-/-TLR4mut mice were detected at 3 hours after E. coli stimulation. The mRNA expression of GSDMD was measured (a) by RT-qPCR. And the expression of GSDMD was detected (b) by Western blot. And relative levels of GSDMD-C to GAPDH (c) and GSDMD-N to GAPDH (d) were analyzed by ImageJ software. Data are presented as . Statistical significance was determined by one-way ANOVA (, ).
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