High-Expressed Macrophage Scavenger Receptor 1 Predicts Severity Clinical Outcome in Transplant Patient in Idiopathic Pulmonary Fibrosis Disease

Figure 2

The expression of MSR1 in the lung tissue samples from PAH and IPF patients. (a) Representative figure of MSR1 expression in the fibrotic lung in the samples from a PAH or IPF patient. Bar: 100 μm. (b) The mean optical density of MSR1-positive cells between PAH and IPF subjects was digitized and analyzed on Image-Pro Plus software. (c) The mean optical density of MSR1-positive cells in IPF subjects with (smoke) or without (none) smoke was analyzed. (d) The mean optical density of MSR1-positive cells in IPF subjects with (K.P-inf, ) or without Klebsiella pneumoniae infection (non-inf, ) was analyzed. (e, f) Representative figure of the expression of IL-13 and arginase-1 (Arg1) in the fibrotic lung in the samples from a PAH or IPF patient. Bar: 100 μm. (g, h) The mean optical density of IL-13- and Arg1-positive cells between PAH and IPF subjects was digitized and analyzed on Image-Pro Plus software. Data are expressed as the for each group, PAH, ; IPF, . and (Student’s -test).

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