Neuroprotective Effect of Taurine against Cell Death, Glial Changes, and Neuronal Loss in the Cerebellum of Rats Exposed to Chronic-Recurrent Neuroinflammation Induced by LPS

Figure 3

Neuroprotective effect of taurine (TAU, 30-100 mg/kg, by gavage; vehicle saline) on the reduction of immunoreactivity for the NeuN protein in the cerebellar cortex (a) and edges of the medullary center (b) regions of rats exposed to chronic-recurrent neuroinflammation induced by the LPS toxin (250 μg/kg, intraperitoneally; vehicle saline). (c) Representative image of the immunostaining obtained through the fluorescence of the selected fields (white bar: 500 μm; yellow bar: 100 μm). was considered to represent a significant difference. denotes a significant difference compared to the vehicle group (VE). # denotes a significant difference compared to the LPS group. Two-way ANOVA followed by Bonferroni’s post hoc. or ### denotes a difference of . Data are expressed as of the mean (SEM), -6 per group.

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