Research Article

Integrated Bioinformatics and Experimental Approaches Identified the Role of NPPA in the Proliferation and the Malignant Behavior of Breast Cancer

Figure 3

The expression of NPPA was impaired in breast cancer tissues. (a–c) The expression pattern of NPPA in IST Online (a), GEPIA (b), or in TCGA (c). (d) The expression of NPPA mRNA in tumor and paratumor tissues (A), in different PAM50 subtypes (B), and in GSE65216 database (C). (e, f) The expression (e) and quantification (f) of NPPA protein level in the Human Protein Atlas with immunohistochemistry. Average optical density (AOD) was used to determine the protein level of NPPA. For the data in (d), (A) was analyzed with paired Student’s -test and the rest were analyzed with Student’s -test. , , and .
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