Single Nucleotide Polymorphisms of IL-33 Gene Correlated with Renal Allograft Fibrosis in Kidney Transplant Recipients

Figure 1

Identification and functional annotation of DEGs and target SNPs between the control and CAD groups. (a) Volcano plots of 162 DEGs were shown between the two groups with 102 upregulated genes and 60 downregulated genes. (b) GO enrichment analysis depicted DEGs were associated with the immune system and inflammatory response. (c) Venn diagram exhibited three intersected genes including IL-33 between DEGs and SNP mutation-related genes. Abbreviations: DEGs: differentially expressed genes; SNP: single nucleotide polymorphism; CAD: chronic renal graft dysfunction; GO: gene ontology.

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