Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein

Figure 8

Quantification of caspase-3 in the hippocampus of APP-overexpressed mice treated with ETAS (200 mg/kg and 1000 mg/kg) and WT mice treated with ETAS (1000 mg/kg) for 1 month, respectively. APP-ETAS (1000 mg/kg and 200 mg/kg) vs. APP saline-treated mice; WT-ETAS (1000 mg/kg) vs. WT saline-treated mice; RFUs: relative fluorescence units. Four mice per group and four sections per mouse were used; green represents capase-3 protein, and blue represents DAPI. Arrows represent fluorescent green staining, indicating positive expression. Magnification is represented ×200.