Correlation of Indoleamine-2,3-Dioxygenase and Chronic Kidney Disease: A Pilot Study

Table 1

Clinical characteristics of CKD patients and non-CKD patients.

	Non-CKD	CKD3	CKD4	CKD5
Gender (male/female)	19/23	38/16	34/15	25/17
Age (years)	^#▲
Uric acid (μmol/l)	^#▲
Albumin (g/l)	^#▲
Prealbumin (mg/l)
FT3 (pmol/l)	^#▲
FT4 (pmol/l)
TSH (mIU/l)
Complement C3 (mg/l)
Complement C4 (mg/l)
Hemoglobin (g/l)	^#▲
Cystatin C (mg/dl)	^#▲
β2-MG (mg/dl)	^#▲
BUN (mmol/l)	^#▲
sCr (μmol/l)	^#▲
Proteinuria (g/24 h)	^#▲
Calcium (mmol/l)	^#▲
Phosphorus (mmol/l)	^#▲
TC (mmol/l)
TG (mmol/l)	^▲
HDL (mmol/l)
LDL (mmol/l)
HbA1c (%)
IgA (mg/l)
IgG (mg/l)
IgM (mg/l)
Tryptophan (μmol/l)	^▲
Kynurenine (μmol/l)	^#▲
IDO	^#▲
CRP (mg/l)
PT (second)
APTT (second)
Fibrinogen (g/l)
DD (μg/ml)

CKD: chronic kidney disease; FT3: free triiodothyronine; FT4: free thyroxine; TSH: thyroid-stimulating hormone; β2-MG: β2-microglobulin; BUN: blood urea nitrogen; sCr: serum creatinine; TC: total cholesterol; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein; IgA: immunoglobulin A; IgG: immunoglobulin G; IgM: immunoglobulin M; IDO: indoleamine-2,3-dioxygenase; CRP: C-reactive protein; PT: prothrombin time; APTT: activated partial thromboplastin time; DD: D-dimer. , non-CKD vs. CKD3; ^#, non-CKD vs. CKD4; ^▲, non-CKD vs. CKD5; ^#▲.