Lipopolysaccharide-Induced Transcriptional Changes in LBP-Deficient Rat and Its Possible Implications for Liver Dysregulation during Sepsis

Figure 2

Distinct transcriptional signature between WT and LBP-deficient rats. (a–c) Transcription profiles of significant differentially expressed genes (DEGs) with log2(fold change) larger than 1.5 at value < 0.01 at 0 h, 6 h, and 24 h, respectively. The labeling condition and DEGs were adapted as previous panels. (d–f) The volcano plot of LPS-induced transcriptional changes between normal and LBP-deficient rats with the time of 0 h, 6 h, and 24 h, respectively. Differential expression genes with log2(fold change) larger than 1.5 at value < 0.05 were colored with blue (downregulated) and red (upregulated).

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