The Role and Function of Regulatory T Cells in <i>Toxoplasma gondii</i>-Induced Adverse Pregnancy Outcomes

<div>Mechanism of maternal-fetal immune regulation. The maternal-fetal interface is composed of CTBs and SYN, formed by the fusion of underlying CTBs. SYN, the key interface between the blood and fetal barrier, is highly resistant to <i>T. gondii</i>. <i>T. gondii</i> rarely goes across SYN. <i>T. gondii</i> infection affects maternal-fetal immune regulation by affecting maternal regulatory immune cells, mainly by inhibiting Tregs. CTBs: cytotrophoblasts; SYN, syncytiotrophoblasts; EVTs: extravillous trophoblasts; Teff cell: effector T; tDC: tolerance-inducing DC; images were created with BioRender.</div>

Journal of Immunology Research

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Figure 2: The Role and Function of Regulatory T Cells in <i>Toxoplasma gondii</i>-Induced Adverse Pregnancy Outcomes 

Journal of Immunology Research

The Role and Function of Regulatory T Cells in Toxoplasma gondii-Induced Adverse Pregnancy Outcomes

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