Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis

Table 2

Permeation parameters for butenafine and butenafine nanoenabled formulations across Strat membrane.

Parameter	BUT-SNEDDS gel	BUT-SNEDDS	Butenafine
Steady-state flux (μg/cm^2/h)
Lag time (min)
Permeability coefficient (cm^2/h)
Diffusion coefficient (cm/h)

indicates statistical significance in comparison to the permeation parameters for butenafine.