Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6

Figure 1

The expression and prognostic information of RIPK4 in OC, as analysed by GEPIA. (a) Large-scale expression profiling of RIPK4 in different types of carcinoma. (b) RIPK4 mRNA expression in OC patients () was significantly higher than that in normal people () (). The red column contains the OC tissues, and the black column contains the normal tissues. (c) To further identify whether RIPK4 expression is related to OC stage, GEPIA was used, which uncovered no significant difference among stages II-IV. (d) Violin plots indicate that the expression level of the RIPK4-201 (ENST00000332512.7) isoform of RIPK4 is significantly higher than that of the RIPK4-202 (ENST00000352483.3) isoform in OC. (e) The Kaplan-Meier plotter demonstrates that the high levels of RIPK4 in OC are associated with a significantly worse survival rate than low levels of RIPK4 expression ().

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