Research Article

Systemic Proteomic Analysis Reveals Distinct Exosomal Protein Profiles in Rheumatoid Arthritis

Figure 6

Integrate analysis based on pathways network enrichment of differentially expressed proteins in rheumatoid arthritis compared with normal controls. Red ball: upregulated differentially expressed protein. Blue ball: downregulated differentially expressed protein. Purple ball: the top 10 enrichment pathways. Larger balls with more markers indicate more enrichment. Different colored lines represent different classification of pathways: red-cellular processes, blue-environmental information processing, green-genetic information processing, purple-human diseases, orange-metabolism, yellow-organismal systems, and brown-drug development. Details for abbreviated protein names are shown in Tables 2 and 3.