STAT1/SOCS1/3 Are Involved in the Inflammation-Regulating Effect of GAS6/AXL in Periodontal Ligament Cells Induced by Porphyromonas gingivalis Lipopolysaccharide In Vitro

Figure 4

Overexpression of AXL reduces P. gingivalis LPS-induced expression of IL-6 and IL-8 in hPDLCs. (a, d) Verification of the efficiency of AXL overexpression at the mRNA (a) and protein (d) levels. (b–e) hPDLCs with or without AXL overexpression were stimulated by 1 μg/mL P. gingivalis LPS for 24 h, and the mRNA (b, c) and protein (d, e) levels of IL-6 and IL-8 were detected.

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