Toll-Like Receptor-Based Strategies for Cancer Immunotherapy

Table 1

A summary of TLR agonists with their corresponding TLR targets.

Target TLR	Agonist	Molecule type	References
TLR2	Pam3Cys	Lipoproteins	[94]
	SMP-105	Cell wall skeleton components	[95, 96]
	CBLB612	Lipopeptide	[97]
TLR3	Poly I:C	Synthetic dsRNA	[98]
	Poly-ICLC		[99]
	Poly-IC12U		[100]
	IPH 3102		[101]
	ARNAX		[102, 103]
TLR4	MPLA	Lipid	[104]
	GLA-SE	Lipid	[105]
	AS04	MPL and aluminum hydroxide	[106]
	OK-432	Low virulence Streptococcus pyogenes strain	[107]
TLR5	CBLB502	Protein	[61]
	M-VM3	Adenoviral vector	[74]
TLR7	Bistriazolyl	Small molecule	[108]
TLR8	VTX1463	Small molecule	[109]
TLR9	MGN1703	Polynucleotide	[61]
	CpG-7909	Oligonucleotide	[110]
	IMO2055		[111]
	dSLIM		[61]
	SD-101		[112, 113]
	KSK-CpG		[88]
	ODN M362		[114]
	CpG-1826		[115]