Inflamm-Aging-Related Cytokines of IL-17 and IFN-γ Accelerate Osteoclastogenesis and Periodontal Destruction

Figure 3

Role of IL-17 (5 μg/ml) or/and IFN-γ (1 μg/ml) on local gingival inflammation in an experimental periodontitis rat model. (a) HE staining showed the periodontal morphology in the interradicular regions of the first maxillary molars of the NC, NS, IL-17, IFN-γ, and IL-17+IFN-γ groups (). (b) Quantitative analysis was performed on the number of inflammatory cells of each group (, ). compared with the NC group, ^# compared with the NS group, and ^& compared with the IL-17+IFN-γ group. T: tooth; AB: alveolar bone.

(a)

(b)