Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression
Table 2
Selected differentially expressed genes (DEGs) between high- and low-risk groups in the training cohort. The genes were selected based on the biological function.
Gene symbol
Gene name
Fold change (log2)
Adjusted value
KYNU
Kynureninase
-1.755
0.00786
IDO1
Indoleamine 2,3-dioxygenase 1
2.326
0.01879
MMP9
Matrix metalloproteinase 9
2.745
<0.0001
MMP1
Matrix metalloproteinase 1
1.761
0.029
MMP12
Matrix metalloproteinase 12
4.562
0.00065
MMP25
Matrix metalloproteinase 25
1.690
0.00054
ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif 2
1.696
0.00251
ADAMDEC1
ADAM like decysin 1
2.863
0.005
ADAM11
ADAM metallopeptidase domain 11
0.975
0.0476
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif 8
0.931
0.0207
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif 4
0.928
0.0047
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
0.962
0.0064
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
