Epitope-Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii

Figure 1

Illustrates the spectrums of the linear conserved surface immunogenic B-cell epitopes. (a) BepiPred Linear Epitope Prediction; the yellow spectrums above and at a cut-off of 0.249 (red line) represent the linear epitopes while the green spectrums exemplify the nonlinear epitopes. (b) Emini surface accessibility prediction; the yellow spectrums above and at a cut-off of 1.000 (red line) illustrate epitopes on the surface whereas green spectrums represent epitopes that are not on the surface. (c) Kolaskar and Tongaonkar antigenicity prediction; the yellow spectrums above and at a cut-off of 1.024 (red line) represent the immunogenic epitopes while green spectrums demonstrate the nonimmunogenic or zerofold epitopes.

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