Epitope-Based Immunoinformatic Approach on Heat Shock 70 kDa Protein Complex of Cryptococcus neoformans var. grubii

Table 6

List of the molecular docking result of the promiscuous epitopes that showed the best binding affinity in terms of their binding energies.

Epitope	Binding MHC molecule	Binding energy ( kcal/mol)
FDYALVQHF	HLA-DRB101:01	-19.03
FFGGKVLNF	HLA-DRB101:01	-17.23
FYRQGAFEL	HLA-DRB101:01	-17.61
FTQLVAAYL	HLA-C12:03	-15.38
FYRQGAFEL	HLA-C12:03	-25.2
YVYDTRGKL	HLA-C12:03	-30.40

Global energy; the energy required to estimate the strength of association between the epitope within the active cleft of MHC molecules; more negative value indicates favored and stable binding of the complex.