SLC2A5 Correlated with Immune Infiltration: A Candidate Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma
Table 2
Correlation analysis between SLC2A5 and related genes and markers of immune cells in TIMER.
Description
Gene markers
LUAD
None
Purity
Cor
value
Cor
value
CD8+ T cell
CD8A
0.403
0
0.286
CD8B
0.343
0.249
T cell
CD3D
0.402
0.279
CD3E
0.41
0.28
CD2
0.408
0.283
B cell
CD19
0.391
0.279
CD79A
0.45
0
0.351
Monocyte
CD86
0.599
0
0.538
0
CSF1R
0.525
0.456
TAM
CCL2
0.427
0
0.361
CD68
0.469
0
0.398
IL10
0.424
0.346
M1 macrophage
NOS2
0.153
0.085
IRF5
0.36
0.287
PTGS2
0.075
0.081
M2 macrophage
CD163
0.517
0
0.458
VSIG4
0.435
0
0.375
MS4A4A
0.438
0
0.368
Neutrophils
CEACAM8
-0.134
-0.158
ITGAM
0.479
0
0.414
CCR7
0.255
0.113
Natural killer cell
KIR2DL1
0.189
0.143
KIR2DL3
0.256
0.187
KIR2DL4
0.464
0.41
KIR3DL1
0.178
0.129
KIR3DL2
0.288
0.23
KIR3DL3
0.245
0.241
KIR2DS4
0.253
0.201
Dendritic cell
HLA-DPB1
0.209
0.084
HLA-DQB1
0.189
0.081
HLA-DRA
0.252
0.139
HLA-DPA1
0.226
0.109
CD1C
-0.062
-0.166
NRP1
0.187
0.163
ITGAX
0.561
0.482
Th1
TBX21
0.366
0.247
STAT4
0.307
0.184
STAT1
0.468
0
0.397
IFNG
0.443
0.361
TNF
0.303
0.207
Th2
GATA3
0.325
0.213
STAT6
-0.138
-0.135
STAT5A
0.39
0.291
IL13
0.057
-0.019
Tfh
BCL6
0.098
0.092
IL21
0.361
0.314
Th17
STAT3
0.104
0.115
IL17A
0.201
0.13
Treg
FOXP3
0.48
0
0.389
CCR8
0.434
0.351
STAT5B
0.209
0.196
TGFB1
0.308
0.219
T cell exhaustion
PDCD1
0.508
0.415
CTLA4
0.485
0
0.388
LAG3
0.499
0
0.413
HAVCR2
0.572
0
0.507
GZMB
0.567
0.491
TAM: tumor-associated macrophage; Th: T helper cell; Tfh: follicular helper T cell; Treg: regulatory T cell; Cor: value of Spearman’s correlation; none: correlation without adjustment; purity: correlation adjusted by purity. ;;.
