Maternal Immune System and State of Inflammation Dictate the Fate and Severity of Disease in Preeclampsia

Figure 1

Expression of Flt1 and endoglin in placental tissue and sera of PPE compared to control cohort. (a) mRNA levels of the Flt1 and Eng transcripts analyzed by real-time polymerase chain reaction (RT-PCR). mRNA abundance quantified with RT-PCR represents quantifications from both control preterm and preterm preeclampsia cohorts with/out smoking history. (b, c) Analysis of Flt1 and Eng at protein levels in placental tissue of preterm preeclampsia compared to control cohort with/out smoking history by Western blotting. Representative Western blot image is shown here. (d) Analysis of the soluble form of Flt1 and Eng in sera of PPE compared to control cohort with/out smoking history by ELISA. Sera were diluted 1 : 10 and quantified with ELISA. The figure is cumulative results of depending upon the subgroup. s denotes smoker, and ns denotes nonsmoker. represents statistically different with value <0.05.

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