Acacetin Protects Myocardial Cells against Hypoxia-Reoxygenation Injury through Activation of Autophagy

<div>Acacetin promotes autophagy to suppress apoptosis of H9c2 cells following H/R injury. H9c2 cells were divided into control, H/R model, and H/R + acacetin (12.5, 25, and 50 <i>μ</i>g/ml) groups. (a–d) Relative protein levels of beclin 1, p62, and LC3-II in each group were measured by Western blot. (e) Immunofluorescence of LC3 II in H9c2 cells as detected by fluorescence microscopy. 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H/R: hypoxia/reoxygenation; LC3-II: microtubule-associated protein 1A/1B-light chain 3.</div>

Journal of Immunology Research

fig4

Figure 4

Figure 4: Acacetin Protects Myocardial Cells against Hypoxia-Reoxygenation Injury through Activation of Autophagy 