NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer

Table 1

GO and KEGG pathway enrichment analyses of DEGs in NSCLC samples.

Term	Pathway description	value	Count in gene set
Downregulated
GO:0030198	Extracellular matrix organization	9.08e-08	12
GO:0043062	Extracellular structure organization	3.96e-07	12
GO:0000280	Nuclear division	2.06e-06	11
GO:0140014	Mitotic nuclear division	2.88e-06	9
GO:0048285	Organelle fission	5.27e-06	11
GO:0000793	Condensed chromosome	7.48e-07	9
GO:0030496	Midbody	1.33e-05	7
GO:0000779	Condensed chromosome, centromeric region	1.57e-05	6
GO:0098687	Chromosomal region	2.82e-05	9
GO:0000794	Condensed nuclear chromosome	8.57e-05	5
GO:0035173	Histone kinase activity	9.26e-07	4
GO:0004222	Metalloendopeptidase activity	1.09e-04	5
GO:0030020	Extracellular matrix structural constituent conferring tensile strength	8.69e-04	3
GO:0008237	Metallopeptidase activity	0.001	5
hsa04115	p53 signaling pathway	8.85e-04	4
Upregulated
GO:0031589	Cell-substrate adhesion	3.11e-13	34
GO:0034329	Cell junction assembly	4.04e-13	28
GO:0034330	Cell junction organization	6.79e-12	29
GO:0003018	Vascular process in circulatory system	2.33e-11	22
GO:0001667	Ameboidal-type cell migration	2.68e-11	36
GO:0005911	Cell-cell junction	2.24e-11	36
GO:0032432	Actin filament bundle	5.17e-11	15
GO:0001725	Stress fiber	1.23e-10	14
GO:0097517	Contractile actin filament bundle	1.23e-10	14
GO:0044449	Contractile fiber part	4.65e-10	23
GO:0003779	Actin binding	1.49e-08	31
GO:0001540	Amyloid-beta binding	1.93e-08	13
GO:0005201	Extracellular matrix structural constituent	1.76e-07	17
GO:0042277	Peptide binding	2.75e-07	23
GO:0033218	Amide binding	6.00e-07	25
hsa04514	Cell adhesion molecules	2.35e-05	14
hsa04670	Leukocyte transendothelial migration	2.95e-05	12
hsa04270	Vascular smooth muscle contraction	3.57e-05	13
hsa04610	Complement and coagulation cascades	5.31e-05	10
hsa04360	Axon guidance	1.97e-04	14

GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; DEGs: differentially expressed genes; NSCLC: non-small-cell lung cancer.