NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer

Table 4

Correlation analysis between NUF2 and immune cell-related genes and markers in TIMER.

Description	Gene markers	LUAD		LUSC
		CD8+ T cell	CD8A	0.16		0.018	0.689
CD8B	0.200			0.078	0.081
T cell (general)	CD3D	0.026	0.554	-0.065	0.144
	CD3E	-0.063	0.148	-0.140
	CD2	-0.046	0.290	-0.080	0.075
B cell	CD19	-0.024	0.584	-0.180
	CD79A	-0.040	0.360	-0.240
Monocyte	CD86	0.024	0.573	-0.230
	CSF1R	-0.17		-0.350
TAM	CCL2	-0.016	0.712	-0.150
	CD68	-0.077	0.074	-0.270
M1 macrophage	NOS2	-0.000	0.998	0.048	0.284
	IRF5	-0.025	0.56	0.004	0.930
	PTGS2	0.047	0.28	-0.230
M2 macrophage	CD163	0.003	0.954	-0.290
	VSIG4	-0.059	0.176	-0.23
	MS4A4A	-0.058	0.181	-0.220
Neutrophils	CEACAM8	-0.420		-0.170
	ITGAM	-0.058		-0.32
	CCR7	-0.220		-0.210
Natural killer cell	KIR2DL1	0.100		-0.042	0.349
	KIR2DL3	0.150		-0.007	0.88
	KIR2DL4	0.41		0.017	0.712
	KIR3DL1	0.1		-0.08	0.072
	KIR3DL2	0.120		0.010	0.821
	KIR3DL3	0.240		0.034	0.441
	KIR2DS4	0.1		-0.053	0.239
Dendritic cell	HLA-DPB1	-0.390		-0.280
	HLA-DQB1	-0.350		-0.220
	HLA-DRA	-0.300		-0.21
	HLA-DPA1	-0.330		-0.24
	BDCA-1 (CD1C)	-0.510		-0.310
	BDCA-4 (NRP1)	-0.098		-0.38
	CD11c (ITGAX	-0.061	0.162	-0.270
Th1	T-bet (TBX21)	-0.010	0.812	-0.083	0.064
	STAT4	-0.056	0.2	-0.270
	STAT1	0.340		0.038	0.398
	IFN-γ (IFNG)	0.310		0.140
	TNF-α (TNF)	-0.060	0.165	-0.220
Th2	GATA3	-0.032	0.46	-0.280
	STAT6	-0.360		-0.130
	STAT5A	-0.180		-0.250
	IL13	-0.029	0.507	-0.007	0.87
Tfh	BCL6	-0.160		-0.027	0.544
	IL21	0.190		0.003	0.954
Th17	STAT3	-0.21		-0.200
	IL17A	0.120		0.069	0.124
Treg	FOXP3	0.009	0.836	-0.190
	CCR8	0.011	0.807	-0.2
	STAT5B	-0.12		0.110
	TGFβ (TGFB1)	-0.260		-0.430
T cell exhaustion	PD-1 (PDCD1)	0.150		-0.087	0.051
	CTLA4	0.11		-0.072	0.109
	LAG3	0.230		0.023	0.601
	TIM-3 (HAVCR2)	0.015	0.723	-0.180
	GZMB	0.430		0.032	0.480

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