Research Article

Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma

Figure 3

Immunological features and drug sensitivity of two EMT molecular subtypes. (a) Heat map depicts the activity of the 50 hallmark pathways in EMT subtypes A and B. (b) Boxplot shows the infiltrations of tumor-infiltrating immune populations in two subtypes. (c) Boxplot depicts the RNA expression of known immune checkpoint molecules in two subtypes. (d) Comparison of the RNA expression of HLA molecules in two subtypes. (e) Comparing the activities of all steps within cancer immunity cycle between subtypes. (f) Boxplot displays the sensitivity to cisplatin and gemcitabine in two subtypes. ; ; and .
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