Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma

Figure 4

Establishment of EMT subtype-relevant coexpression modules in the TARGET cohort. (a) Hierarchical clustering dendrogram of osteosarcoma individuals as well as the matched EMT molecular subtypes. (b) Analyses of network topology and average network connectivity under diverse soft-threshold powers (β). The red line is indicative of a correlation coefficient of 0.85. (c) Clustering dendrogram with dissimilarity in accordance with topological overlapping, along with designed module colors. (d) The interaction network between modules and EMT molecular subtypes. Each column is indicative of EMT molecular subtype while each row is indicative of a coexpression module. The number in the rectangle displays the correlation coefficient and value.

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