Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma

Figure 6

Development of EMT score for osteosarcoma prognosis in the TARGET cohort. (a) Heat map depicts the expression of each gene from EMT score in each osteosarcoma specimen. Red is indicative of upregulation; and blue is indicative of downregulation. (b) The distribution of risk score among osteosarcoma individuals. Vertical dotted line is indicative of the median value of EMT score. (c) The distribution of survival status of high- and low-risk subgroups. (d) Kaplan-Meier survival analyses for two subgroups. (e) ROC curves at one-, three-, and five-year survival in accordance with EMT score. (f) C-index of our EMT model and previously published two EMT models from Zhang et al. and Peng et al.

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