Knocking Out of CEACAM1 Can Reduce Oxidative Stress and Promote Cell Proliferation in the HPMVECs under Hypoxia

Figure 4

Cell cycle detection with flow cytometry and cell proliferation was measured through CCK8 assays. (a) More of the HPMVECs grown under OGD/R conditions were found to be in G0/G1 or G2/M phase, while fewer were in S phase than in the control group. (b) The cell number of CEACAM1^-/- group in G0/G1 or G2/M phase was reduced, while S phase increased compared to the NC group. (c) The cell viability measured by CCK8 assays of OGD/R group did not differ from the NC group, but was significantly lower than the CEACAM1^-/- group.

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(b)

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