Journal of Immunology Research

Research Article

Promising Neutrophil-Associated Biomarkers in Lung Diseases of Patients with Antisynthetase Syndrome and Dermatomyositis

Table 2

Laboratory variants of the ASS and DM patients.
VariablesAllASSDM value
CK (U/L)66.5 (26.0, 383.8)63.5 (25.3, 344.5)142 (33, 623.3)0.209
ESR (mm/h)24.0 (13.5, 36.3)21.5 (15, 31.5)28 (9.5, 37.3)0.578
CRP (mg/L)6.7 (4.7, 10.6)8.1 (4.7, 10)6.4 (4.5, 11.3)0.324
LDH (U/L)293.5 (232.8, 471.3)285.0 (224.5, 337.5)322.0 (258.0, 549.0)0.333
WBC (×109/L)7.1 (5.2, 9.1)7.9 (5.9, 9.4)6.1 (4.4, 8.4)0.073
Lymphocyte (×109/L)0.9 (0.5, 1.3)1.2 (0.9, 1.5)0.6 (0.4, 1.1)0.03
Neutrophil (×109/L)5.3 (3.6, 7.2)6.2 (4.2, 8.1)4.6 (3.2, 6)0.077
FVC (%)81.2 (66.6, 92.2)74.3 (64.8, 83.9)84 (66.6, 105)0.164
DLCO (%)71.4 (48.9, 83.8)48.3 (35.5, 58.4)81.8 (77, 86.3)<0.0001
Disease duration (month)3.0 (2.4, 6.0)3 (2.1, 6)3 (2.8, 8.4)0.401
Myositis antibodies,
 Anti-Jo-113130
 Anti-OJ220
 Anti-EJ440
 Anti-PL-7110
 Anti-PL-12330
 Anti-MDA512012
 Anti-NXP-2303
 Anti-TIF-1γ404
 Anti-Mi-2101
 Anti-Ro-52 (alone)404
Anti-Ro-52 (with other antibodies)261610
Negative202
Values are (%) or the quartile method. for comparison between ASS group vs. DM group using an independent sample test or the Wilcoxon rank-sum test.