Research Article

Different Airway Inflammatory Phenotypes Correlate with Specific Fungal and Bacterial Microbiota in Asthma and Chronic Obstructive Pulmonary Disease

Figure 3

Differential taxa of fungi between eosinophilic and noneosinophilic inflammatory phenotypes. At genus and species levels, the LEfSe analysis between (a) EA vs. NEA and (b) EC vs. NEC. The LDA threshold was set at 3.0, and taxa with relative abundance less than 0.5% were filtered out. The fungal genera predicted by random forest analysis for classifying (c) asthma and (d) COPD subjects into eosinophilic and noneosinophilic inflammatory phenotypes. Random forest models were established against a 10-fold cross-validation.
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